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On-line TOC, BORON Analyzers

M9 Series TOC Analyzers

Sievers M9 Laboratory Total Organic Carbon (TOC) Analyzer

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Superior productivity

Tools that boost productivity are essential to managing your chaotic workday. The new Sievers M9 Total Organic Carbon (TOC) Analyzers offer you time-tested dependability with faster-than-ever analysis to help you reach the peak of productivity.

An unequalled level of efficiency and flexibility

  • Providing readings in only two minutes, the M9 analyzes TOC 50% faster than the 900 Series Analyzers.
  • Automated calibration, verification, and data analysis enable unattended operation.
  • Combine with the optional high-capacity GE Autosampler, featuring random access capability and up to 120 sample positions.
  • The Autoreagent feature automatically establishes optimal flow rates for each sample.
  • Saved methods are now available at the instrument.

Easy to use and cost-effective

  • Streamlined protocols are faster to set up and save.
  • Graphically enhanced “fast-links” for informative error and alert messages allow independent troubleshooting and restoration of instrument memory.
  • The M9 Analyzer’s database structure allows more useful ways to arrange, search and query data.
  • There is no need for external reagents or gas supplies.
  • The M9 requires only a few hours of preventive maintenance per year, and calibration is stable for 12 months.
  • It's large, color, touch-screen display provides intuitive menus.
  • It's space-saving profile (19.2-cm/7.6-in wide) efficiently uses valuable bench space.

Simplifying Conductivity Analysis

Electrical Conductivity in water is a measure of the ion-facilitated electron flow through it. Water molecules dissociate into ions as a function of pH and temperature and result in a very predictable Conductivity.

The new M9 Laboratory and Portable Analyzers offer sample conductivity measurement for unique pharmaceutical applications. This new analyzer enables simple Stage 1 analysis or cleaning validation rinse sample evaluation with results in only two minutes. Sample Conductivity saves users time, eliminates sample-handling issues and minimizes potential failures. Other processes require two separate technologies to measure TOC and Conductivity. Using one sample vial, the Sievers M9 TOC Analyzers simultaneously analyze and report two discrete results for TOC and Conductivity.

Compliance with the Japanese pharmaceopeia 16 (JP16) and other global pharmacopeias

The Sievers M9 Series and the Sievers 500 RL now offer integrated firmware and software support to meet Japanese Pharmacopeia 16 (JP16), JP<2.59> TOC Test and JP<2.51> Conductivity Test requirements for Purified Water (PW) and Water for Injection (WFI). The JP <2.59> TOC standard requires different compounds and calculations for calibration and system suitability testing than those specified in the USP and EP monographs.

The Sievers M9 and 500 RL Series TOC Analyzers support all other major global pharmacopeias, including the United States Pharmacopeia (USP), European Pharmacopeia (EP), Chinese Pharmacopeia (CP), and the Indian Pharmacopeia (IP).

Unique TOC technology

The UV/persulfate oxidation method and unique Membrane Conductometric Detection Technology deliver unmatched accuracy and precision across the M9 Laboratory Analyzer’s 0.03 parts per billion (ppb) to 50 parts per million (ppm) operating range. The M9 Laboratory Analyzer meets or exceeds today's most common pharmaceutical regulatory requirements. It is ideal for routine analysis of TOC samples, and is also well suited for testing laboratories that analyze a variety of sample matrices and concentrations.

Stage 1 Sample Conductivity Analysis

Electrical Conductivity in water is a measure of the ion-facilitated electron flow through it. Water molecules dissociate into ions as a function of pH and temperature and result in a very predictable Conductivity.

The new M9 Laboratory Analyzer offers Sample Conductivity measurement. Enabling simple Stage 1 analysis with results in only two minutes, Sample conductivity saves users time, eliminates sample-handling issues and minimizes potential failures. Other processes require two separate technologies to measure TOC and Conductivity. Using one sample vial, the Sievers M9 TOC Analyzers simultaneously analyze and report two discrete results for TOC and Conductivity.

Productivity

  • Two-minute analysis time
  • Automated operations, such as calibration and data analysis
  • Autoreagent feature automatically establishes optimal flow rates for each sample

Low Maintenance and Operating Costs

  • No external reagent or gas supplies are required, saving valuable lab space, time, and money.
  • Internal reagent packs that can be installed in minutes to achieve three to six months of uninterrupted service, depending on the application.
  • The M9 Series Analyzers typically require just a few hours per year of preventive maintenance.
  • It's modular design facilitates quick consumables replacement and preventive maintenance.

12-month calibration stability

The M9 Laboratory Analyzer offers 12-month calibration stability, unlike competing analyzers that require weekly or even daily calibration. Users can select from a single- and multi-point calibration. To further simplify operation, calibration calculations are performed and constants updated automatically.

Simple and intuitive

  • Large, color, touch-screen display
  • Saved methods available at the instrument
  • At-a-glance consumables status
  • Trend data displays in tabular or graphical form

Expanded Data Access

The M9 Laboratory TOC Analyzer uses a standard USB port to communicate with the optional Autosampler and to download data in a file compatible with Microsoft Excel.

Operating Specifications*
Range 0.03 ppb to 50 ppm
Precision < 1% RSD
Accuracy ± 2% or ± 0.5 ppb, whichever is greater
Display Readout 3 significant digits
Sample Type Autosampler or discrete grab sample
Calibration Typically stable for 12 months
Analysis Time 2 minutes (4 seconds with the optional Turbo mode)
Sample Temperature 5–95 °C (41–203 °F)
Ambient Temperature 5–40 °C (41–104 °F)
Instrument Sample
Flow Rate
0.5 mL/min
Analyzer Specifications
Outputs USB device port (1); USB host ports (3); Ethernet
Display 7" WVGA 800X480 pixel, Color LCD with touch-screen
Power 100 - 240 V~, 50 -60 Hz, 100 VA
Fuses Replace with same type and size fuse: T 1.6 A 350 VAC Fuse (Slow Blow), size 5 X 20 mm appliance inlet
Dimensions H: 42.2 cm (16.6 in); W: 24.6 cm (9.7 in); D: 40.0 cm (15.8 in)
Weight 9.4 kg (20.6 lb)
Safety Certifications ETL, CE (see Declaration of Conformity)
Sample Conductivity (Optional)
Raw Conductivity Range 0.01 to 2,000 μS/cm
Conductivity Accuracy ±0.005 μS/cm or ±1%.whichever is greater
Precision <0.25% RSD
Environment
Maximum Relative Humidity 0 - 95%, non-condensing
Maximum Altitude 3,000 m (9.800 ft)
Pollution Degree 2

 

* Stated analytical performance is achievable under controlled laboratory conditions that minimize operator and standards errors.

The Sievers M9 Turbo is fast! Specifications include an analysis time of 4 seconds and a wide analytical range of 0.20 parts per billion (ppb) to 10 parts per million (ppm) of TOC. The Sievers M9 Laboratory Turbo is:

  • Sensitive enough to detect the smallest changes in reclaim TOC
  • Robust enought to maintain accuracy even at 10 ppm
  • Fast enough to outperform all other reclaim TOC analyzers and provide up-to-the-second results
  • Immune to false positives and false negatives that trouble non-membrane-based TOC analyzers
Operating Specifications*
Range 0.20 ppb to 10 ppm
Precision 2% RSD
Accuracy ±3%
Display Readout 3 significant digits
Sample Type Grab and Autosampler
Calibration Typically stable for 12 months
Analysis Time 4 seconds
Response Time 3.25 Minutes
Sample Temperature 5–95 °C (41–203 °F)
Ambient Temperature 10–40 °C (50–104 °F)
Sample Pressure** Up to 100 psi
Instrument Sample
Flow Rate
1.1. ml/min
Analyzer Specifications
Outputs USB device port (1); USB host ports (3); Ethernet
Display 7" WVGA 800X480 pixel, Color LCD with touch-screen
Power 100 - 240 V~, 50 -60 Hz, 100 VA
Fuses Replace with same type and size fuse: T 1.6 A 350 VAC Fuse (Slow Blow), size 5 X 20 mm appliance inlet
Dimensions H: 42.2 cm (16.6 in); W: 24.6 cm (9.7 in); D: 40.0 cm (15.8 in)
Weight 9.4 kg (20.6 lb)
Safety Certifications ETL, CE
Consumables
UV Lamp 6 months
Acid Reagent As needed, typically 6 months
Oxidizer Reagent As needed, typically 3-month stability; available in 150- or 300-mL cartridge

 

*Stated analytical performance is achievable under controlled laboratory conditions that minimize operator and standards errors.
**If the sample temperature and pressure are above 60 °C and 100 psi, the M9 Analyzer model with the stainless steel iOS is required.

GE Autosampler - The GE Autosampler provides random access capability with high sample capacity. Working in conjunction with DataPro2 also gives users full sampling flexibility with custom sample protocols and user-defined sampling capabilities.

GE Autosampler

DataPro2 Software - The Sievers DataPro2 Software integrates the GE Autosampler with the M9 Laboratory Analyzer to offer productivity-enhancing features such as automated calibration and validation protocols. DataPro2 gives users full sampling flexibility with custom sample protocols and user-defined sampling capabilities. View our series of informational videos on YouTube.

DataPro2 Videos
 

GE Autosampler Rinse Station - The optional Rinse Station flushes the sample inlet system and needle with a flowing water source, maximizing analytical performance of samples of varying concentrations.

Wash Station Installed
 

DataGuard Software - The optional DataGuard software provides full compliance support for 21 CFR Part 11 requirements for electronic records in pharmaceutical applications. DataGuard is available within the DataPro2 Autosampler software and is integrated into the laboratory, portable, and on-line models for standalone operation.

Wash Station Installed
 

M9 Laboratory Turbo - This feature takes the 2-minute analysis time in the standard M9 Laboratory Analyzer down to a 4-second analysis time saving users hours of time on each GE Autosampler run of 63 vials. Turbo can also be used in grab sample mode saving time even on individual samples.

 
 

Inorganic Carbon Remover (ICR) - Integrated inside the M9 instrument, the optional ICR reduces inorganic carbon levels in sample streams with high IC/TOC ratios to produce more accurate TOC results.

 
 
 
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